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Title: MNase and HpaII sensitivity assays in MCF7 breast cancer cells      
dateReleased:
02-25-2015
description:
DNA are packaged into nucleosomes and chromatin. We performed incomplete MNase digestion of chromatin to identify nucleosome-free regions that may indicate active promoters and regulatory regions. Additionally, HpaII digestion was performed which cleaves CCGG sites when the internal C remains unmodified. The hypomethylation state and nuclease sensitivity of the chromatin are indicators of transcription regulatory regions. Four other data sets from this study were also deposited at ArrayExpress under accession numbers E-MTAB-1935, E-MTAB-1952, E-MTAB-1961 and E-MTAB-2014.
privacy:
not applicable
aggregation:
instance of dataset
ID:
E-MTAB-1958
refinement:
raw
keywords:
functional genomics
dateModified:
07-04-2016
availability:
available
types:
gene expression
name:
Homo sapiens
accessURL: https://www.ebi.ac.uk/arrayexpress/files/E-MTAB-1958/E-MTAB-1958.raw.1.zip
storedIn:
ArrayExpress
qualifier:
gzip compressed
format:
TXT
accessType:
download
authentication:
none
authorization:
none
accessURL: https://www.ebi.ac.uk/arrayexpress/files/E-MTAB-1958/E-MTAB-1958.processed.1.zip
storedIn:
ArrayExpress
qualifier:
gzip compressed
format:
TXT
accessType:
download
authentication:
none
authorization:
none
abbreviation:
EBI
homePage: http://www.ebi.ac.uk/
ID:
SCR:004727
name:
European Bioinformatics Institute
homePage: https://www.ebi.ac.uk/arrayexpress/
ID:
SCR:002964
name:
ArrayExpress

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