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Title: Identification of PARD3 signature on PARD3 deficient H157 cell line, reconstituting the expression of PARD3 gene, with a wt and a mutant form      
dateReleased:
05-19-2015
description:
To development our gene expression approach, we have employed whole genome microarray expression profiling as a discovery platform to identify genes potentialy regulated by the polarity protein PAR3. Human SCC cell line, NCI-H157 (H157), has a big deletion at PARD3 locus and showed no PAR3 protein expression. This cell line was used as a model in which we restored the expression of PAR3 (wt or mutant form). Afterwards, this model was used to identify PARD3 signature on Human SCC. There are triplicates of each sample. We compare the effects in gene expression between the different situations: no PARD3 expression in the cell, expression of the mutant form of PARD3 gene and expression of the PARD3 wt form in the cells.
privacy:
not applicable
aggregation:
instance of dataset
ID:
E-GEOD-51506
refinement:
raw
alternateIdentifiers:
51506
keywords:
functional genomics
dateModified:
05-24-2015
availability:
available
types:
gene expression
name:
Homo sapiens
ID:
A-GEOD-16699
name:
Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381
accessURL: https://www.ebi.ac.uk/arrayexpress/files/E-GEOD-51506/E-GEOD-51506.raw.1.zip
storedIn:
ArrayExpress
qualifier:
gzip compressed
format:
TXT
accessType:
download
authentication:
none
authorization:
none
accessURL: https://www.ebi.ac.uk/arrayexpress/files/E-GEOD-51506/E-GEOD-51506.processed.1.zip
storedIn:
ArrayExpress
qualifier:
gzip compressed
format:
TXT
accessType:
download
authentication:
none
authorization:
none
accessURL: https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE51506
storedIn:
Gene Expression Omnibus
qualifier:
not compressed
format:
HTML
accessType:
landing page
primary:
true
authentication:
none
authorization:
none
abbreviation:
EBI
homePage: http://www.ebi.ac.uk/
ID:
SCR:004727
name:
European Bioinformatics Institute
homePage: https://www.ebi.ac.uk/arrayexpress/
ID:
SCR:002964
name:
ArrayExpress

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