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Title: CIT-CHEF      
dateReleased:
06-15-2015
description:
Fibrolamellar hepatocellular carcinoma (FLC) is a rare type of primary liver cancer that often arises in children, adolescents and young adults. At the pathological level, FLC display pure morphology or can present with mixed morphology involving a conventional HCC component. Owing to the rarity of the disease, its genetic landscape is fully unknown. Pure FLC showed less chromosomic aberrations than mixed FLC and hepatocellular carcinoma arising in non-cirrhotic liverᄉ. Nevertheless; they displayed more gains in 16q23 and more LOH in 21q22. We also analyzed the mutational landscape of 8 FLC by whole-exome sequencing and showed mutations in the coagulation pathway.
privacy:
not applicable
aggregation:
instance of dataset
ID:
E-MTAB-2675
refinement:
raw
keywords:
functional genomics
dateModified:
06-20-2014
creators:
Nabila Elarouci
availability:
available
types:
gene expression
name:
Homo sapiens
ID:
A-GEOD-6986
name:
Illumina HumanCNV370-Duov1 DNA Analysis BeadChip (HumanCNV370v1)
accessURL: https://www.ebi.ac.uk/arrayexpress/files/E-MTAB-2675/E-MTAB-2675.raw.1.zip
storedIn:
ArrayExpress
qualifier:
gzip compressed
format:
TXT
accessType:
download
authentication:
none
authorization:
none
accessURL: https://www.ebi.ac.uk/arrayexpress/files/E-MTAB-2675/E-MTAB-2675.processed.1.zip
storedIn:
ArrayExpress
qualifier:
gzip compressed
format:
TXT
accessType:
download
authentication:
none
authorization:
none
abbreviation:
EBI
homePage: http://www.ebi.ac.uk/
ID:
SCR:004727
name:
European Bioinformatics Institute
homePage: https://www.ebi.ac.uk/arrayexpress/
ID:
SCR:002964
name:
ArrayExpress

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