Mountain View
biomedical and healthCAre Data Discovery Index Ecosystem
help Advanced Search
Title: Stretch-dependent genes in vascular smooth muscle cells      
dateReleased:
07-01-2015
description:
Vascular smooth muscle cells (VSMCs) respond to biomechanical stretch with specific changes in gene expression which govern the phenotype of these cells. The mechanotransducer zyxin is a potential candidate for regulating the expression of such genes. Using microarrays, we compared stretch-induced gene expression in wild type and zyxin-null VSMCs to define such changes in detail. Wild type (WT) and zyxin-null VSMCs were stretched at 10% cyclic elongation for 6 hours and the changes in gene expression were compared under static and stretched conditions. Up to 3 biological replicates were used for each of the 4 sample types.
privacy:
not applicable
aggregation:
instance of dataset
ID:
E-GEOD-60447
refinement:
raw
alternateIdentifiers:
60447
keywords:
functional genomics
dateModified:
08-19-2015
availability:
available
types:
gene expression
name:
Mus musculus
ID:
A-GEOD-18615
name:
[Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array [CDF: Mouse4302_Mm_ENTREZG.cdf Brainarray version 17.0.0]
accessURL: https://www.ebi.ac.uk/arrayexpress/files/E-GEOD-60447/E-GEOD-60447.raw.1.zip
storedIn:
ArrayExpress
qualifier:
gzip compressed
format:
TXT
accessType:
download
authentication:
none
authorization:
none
accessURL: https://www.ebi.ac.uk/arrayexpress/files/E-GEOD-60447/E-GEOD-60447.processed.1.zip
storedIn:
ArrayExpress
qualifier:
gzip compressed
format:
TXT
accessType:
download
authentication:
none
authorization:
none
accessURL: https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE60447
storedIn:
Gene Expression Omnibus
qualifier:
not compressed
format:
HTML
accessType:
landing page
primary:
true
authentication:
none
authorization:
none
abbreviation:
EBI
homePage: http://www.ebi.ac.uk/
ID:
SCR:004727
name:
European Bioinformatics Institute
homePage: https://www.ebi.ac.uk/arrayexpress/
ID:
SCR:002964
name:
ArrayExpress