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Title: Comparison against 186 canid whole genome sequences reveals survival strategies of an ancient clonally transmissible canine tumor      
dateReleased:
07-30-2015
description:
Whole genome sequencing of CTVT, breed dogs, and wild canids reveals pathways that are important in cancer cell survival. Comparison of these mutations with breed dogs shows that the original tumor came from a dog very similar to one of the modern Arctic breeds. DNA was collected from pedigreed dogs of the Alaskan Malamute (AMAL) and Siberian Husky (HUSK) breeds living in North America. SNPs were genotyed using the Illumina CanineHD SNP chip. These SNPs were compared to published data and seqeunced mutations from CTVT by principal component alnalysis to identify the breed of the CTVT originator.
privacy:
not applicable
aggregation:
instance of dataset
ID:
E-GEOD-70454
refinement:
raw
alternateIdentifiers:
70454
keywords:
functional genomics
dateModified:
08-20-2015
availability:
available
types:
gene expression
name:
Canis lupus familiaris
ID:
A-GEOD-17481
name:
Illumina CanineHD BeadChip
accessURL: https://www.ebi.ac.uk/arrayexpress/files/E-GEOD-70454/E-GEOD-70454.raw.1.zip
storedIn:
ArrayExpress
qualifier:
gzip compressed
format:
TXT
accessType:
download
authentication:
none
authorization:
none
accessURL: https://www.ebi.ac.uk/arrayexpress/files/E-GEOD-70454/E-GEOD-70454.processed.1.zip
storedIn:
ArrayExpress
qualifier:
gzip compressed
format:
TXT
accessType:
download
authentication:
none
authorization:
none
accessURL: https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE70454
storedIn:
Gene Expression Omnibus
qualifier:
not compressed
format:
HTML
accessType:
landing page
primary:
true
authentication:
none
authorization:
none
abbreviation:
EBI
homePage: http://www.ebi.ac.uk/
ID:
SCR:004727
name:
European Bioinformatics Institute
homePage: https://www.ebi.ac.uk/arrayexpress/
ID:
SCR:002964
name:
ArrayExpress

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