Systematic Identification of Factors Crucial for Provirus Silencing in Embryonic Stem Cells (RNA-seq)

Title:

Systematic Identification of Factors Crucial for Provirus Silencing in Embryonic Stem Cells (RNA-seq)

dateReleased:	09-14-2015
description:	Our study reports the first genome-wide atlas of functional nodes that mediate proviral silencing in ESCs. It provides evidences for the comprehensive, interconnected and multi-layered genetic/epigenetic machineries by which ESCs maintain the repressive state of provirus and ERVs. RNA-seq analysis to determine the regulated endogenous retroviruses by Histone chaperones (Chaf1a/b), sumoylation factors (Sumo2/ Ube2i/Sae1/Uba2/Senp6) and chromatin modifiers (Trim28/Eset/Atf7ip)
privacy:	not applicable
aggregation:	instance of dataset
ID:	E-GEOD-70863
refinement:	raw
alternateIdentifiers:	70863
keywords:	functional genomics
dateModified:	09-20-2015
availability:	available
types:	gene expression

name:	Mus musculus

landingPage:	https://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-70863

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accessURL:	https://www.ebi.ac.uk/arrayexpress/files/E-GEOD-70863/E-GEOD-70863.processed.1.zip
storedIn:	ArrayExpress
qualifier:	gzip compressed
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authentication:	none
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accessURL:	https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE70863
storedIn:	Gene Expression Omnibus
qualifier:	not compressed
format:	HTML
accessType:	landing page
primary:	true
authentication:	none
authorization:	none

abbreviation:	EBI
homePage:	http://www.ebi.ac.uk/
ID:	SCR:004727
name:	European Bioinformatics Institute

homePage:	https://www.ebi.ac.uk/arrayexpress/
ID:	SCR:002964
name:	ArrayExpress

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