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Title: Bortezomib resistance in CCRF-CEM cell line [CGH]      
dateReleased:
11-04-2015
description:
Bortezomib is a proteasome inhibitor used in severel different hematological malignancies. Resistance to this drug is still poorly understood. In order get more insight in the resistance mechanism, we developed several bortezomib resistant subclones of the CCRF-CEM T-ALL cell line. On these subclones comparative Genome hybridization (arrayCGH) for DNA copy number analysis gene expression and micro-RNA expression arrays were performed. We performed comparative Genome hybridization (arrayCGH) for DNA copy number analysis on four different bortezomib resistant subclones of the CCRF-CEM cell line. The resistant subclones were compared to the parental CCRF-CEM wildtype cell line and reference DNA.
privacy:
not applicable
aggregation:
instance of dataset
ID:
E-GEOD-74633
refinement:
raw
alternateIdentifiers:
74633
keywords:
functional genomics
dateModified:
12-02-2015
availability:
available
types:
gene expression
name:
Homo sapiens
ID:
A-GEOD-8687
name:
Agilent SurePrint G3 CGH array (4X180K) CCA_VUMC design AMADID#022522
accessURL: https://www.ebi.ac.uk/arrayexpress/files/E-GEOD-74633/E-GEOD-74633.raw.1.zip
storedIn:
ArrayExpress
qualifier:
gzip compressed
format:
TXT
accessType:
download
authentication:
none
authorization:
none
accessURL: https://www.ebi.ac.uk/arrayexpress/files/E-GEOD-74633/E-GEOD-74633.processed.1.zip
storedIn:
ArrayExpress
qualifier:
gzip compressed
format:
TXT
accessType:
download
authentication:
none
authorization:
none
accessURL: https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE74633
storedIn:
Gene Expression Omnibus
qualifier:
not compressed
format:
HTML
accessType:
landing page
primary:
true
authentication:
none
authorization:
none
abbreviation:
EBI
homePage: http://www.ebi.ac.uk/
ID:
SCR:004727
name:
European Bioinformatics Institute
homePage: https://www.ebi.ac.uk/arrayexpress/
ID:
SCR:002964
name:
ArrayExpress

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