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Title: Transcription profiling by high throughput sequencing of human, gastric adenocarcinoma, gastrointestinal tract (lamina propria) macrophage with wildtype and EZH2 knockdown cells to investigate annexin AG      
dateReleased:
11-07-2015
description:
Polycomb repressive complexes (PRC) play a critical role during tumorigenesis and development. The histone methyltransferase Enhancer of Zeste homologue 2 (EZH2), as a core component of PRC2, is frequently overexpressed in a wide variety of cancers. EZH2-mediated gene silencing contributes to carcinogenesis. To further the understanding of the EZH2 biology in gastric cancer, here we performed transcriptome analyses and identified EZH2-responsive genes upon EZH2 knockdown by RNA-seq.
privacy:
not applicable
aggregation:
instance of dataset
ID:
E-MTAB-3227
refinement:
raw
dateSubmitted:
11-07-2014
keywords:
functional genomics
dateModified:
07-08-2016
creators:
jun wu
availability:
available
types:
gene expression
name:
Homo sapiens
name:
strain or line design
accessURL: https://www.ebi.ac.uk/arrayexpress/files/E-MTAB-3227/E-MTAB-3227.raw.1.zip
storedIn:
ArrayExpress
qualifier:
gzip compressed
format:
TXT
accessType:
download
authentication:
none
authorization:
none
accessURL: https://www.ebi.ac.uk/arrayexpress/files/E-MTAB-3227/E-MTAB-3227.processed.1.zip
storedIn:
ArrayExpress
qualifier:
gzip compressed
format:
TXT
accessType:
download
authentication:
none
authorization:
none
abbreviation:
EBI
homePage: http://www.ebi.ac.uk/
ID:
SCR:004727
name:
European Bioinformatics Institute
homePage: https://www.ebi.ac.uk/arrayexpress/
ID:
SCR:002964
name:
ArrayExpress

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