dateReleased: |
11-11-2015
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description: |
Appetite is largely controlled by hypothalamic neurons. Variation near the Negr1 gene has been significantly associated with increased body mass in multiple human genome-wide association studies. Accordingly, we ablated Negr1 in the hypothalamus of mice and demonstrated this was sufficient to generate a metabolic phenotype. To investigate the molecular mechanisms through which Negr1 influences feeding behaviour, we performed paired-end RNAseq on the Illumina platform in hypothalamic tissue from Negr1 knockout and control mice This data is part of a pre-publication release. For information on the proper use of pre-publication data shared by the Wellcome Trust Sanger Institute (including details of any publication moratoria), please see
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privacy: |
not applicable
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aggregation: |
instance of dataset
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ID: |
E-ERAD-404
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refinement: |
raw
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keywords: |
functional genomics
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dateModified: |
05-17-2016
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creators: |
The Wellcome Trust Sanger Institute
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availability: |
available
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types: |
gene expression
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name: |
Mus Musculus
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accessURL: | https://www.ebi.ac.uk/arrayexpress/files/E-ERAD-404/E-ERAD-404.raw.1.zip![]() |
storedIn: |
ArrayExpress
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qualifier: |
gzip compressed
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format: |
TXT
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accessType: |
download
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authentication: |
none
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authorization: |
none
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accessURL: | https://www.ebi.ac.uk/arrayexpress/files/E-ERAD-404/E-ERAD-404.processed.1.zip![]() |
storedIn: |
ArrayExpress
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qualifier: |
gzip compressed
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format: |
TXT
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accessType: |
download
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authentication: |
none
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authorization: |
none
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abbreviation: |
EBI
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homePage: | http://www.ebi.ac.uk/ |
ID: |
SCR:004727
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name: |
European Bioinformatics Institute
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homePage: | https://www.ebi.ac.uk/arrayexpress/ |
ID: |
SCR:002964
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name: |
ArrayExpress
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