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Title: Mycobacterium tuberculosis H37Rv transcriptional response to antibacterial agents      
dateReleased:
11-11-2015
description:
Bacteria commonly adapt to stresses by altering gene expression. To understand the response of M. tuberculosis (MTB) to various antibacterial agents, we performed transcriptomics on MTB bacilli exposed to several test compounds as well as known drugs (capreomycin, cycloserine, ethionamide, isoniazid, kanamycin, moxifloxacin, PA-824, rifampicin, streptomycin). Bacteria were exposed for 16 hrs to various concentrations of each drug (different multiples of the compound's MIC), as noted in the title of each sample. RNA was isolated and applied to arrays provided by TIGR under the NIAID contract N01-AI-15447
privacy:
not applicable
aggregation:
instance of dataset
ID:
E-GEOD-71200
refinement:
raw
alternateIdentifiers:
71200
keywords:
functional genomics
dateModified:
11-30-2015
availability:
available
types:
gene expression
name:
Mycobacterium tuberculosis
ID:
A-GEOD-5774
name:
JCVI PFGRC Mycobacterium tuberculosis 22K v4 array designed primarily based on strain H37Rv
accessURL: https://www.ebi.ac.uk/arrayexpress/files/E-GEOD-71200/E-GEOD-71200.raw.1.zip
storedIn:
ArrayExpress
qualifier:
gzip compressed
format:
TXT
accessType:
download
authentication:
none
authorization:
none
accessURL: https://www.ebi.ac.uk/arrayexpress/files/E-GEOD-71200/E-GEOD-71200.processed.1.zip
storedIn:
ArrayExpress
qualifier:
gzip compressed
format:
TXT
accessType:
download
authentication:
none
authorization:
none
accessURL: https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE71200
storedIn:
Gene Expression Omnibus
qualifier:
not compressed
format:
HTML
accessType:
landing page
primary:
true
authentication:
none
authorization:
none
abbreviation:
EBI
homePage: http://www.ebi.ac.uk/
ID:
SCR:004727
name:
European Bioinformatics Institute
homePage: https://www.ebi.ac.uk/arrayexpress/
ID:
SCR:002964
name:
ArrayExpress