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Title: miRNA expression in healthy carriers of heterozygous BRCA1 mutation and healthy WT controls      
dateReleased:
12-31-2015
description:
In order to investigate whether carriers of BRCA1 heterozygous mutation show altered miRNA expression profiles, we established a panel of lymphoblastoid cell lines (LCLs) harboring either mutated or WT BRCA1 (control) and investigated their miRNA expression profiles. We were especially interested whether we find differences in miRNA expression between carriers of missense versus truncating mutation in BRCA1 gene. We evaluated the miRNA expression in a panel of 21 non-treated lymphoblastoid cell lines (LCLs). Among them, 6 LCLs with WT BRCA1, 5 LCLs carrying missense mutation in BRCA1, and 10 LCLs harboring truncating mutation in BRCA1 were included in this study.
privacy:
not applicable
aggregation:
instance of dataset
ID:
E-GEOD-60444
refinement:
raw
alternateIdentifiers:
60444
keywords:
functional genomics
dateModified:
01-18-2016
availability:
available
types:
gene expression
name:
Homo sapiens
ID:
A-GEOD-19083
name:
miRCURY LNA microRNA Array - 7th generation - hsa, mmu & rno [miRBase 19.0]
accessURL: https://www.ebi.ac.uk/arrayexpress/files/E-GEOD-60444/E-GEOD-60444.raw.1.zip
storedIn:
ArrayExpress
qualifier:
gzip compressed
format:
TXT
accessType:
download
authentication:
none
authorization:
none
accessURL: https://www.ebi.ac.uk/arrayexpress/files/E-GEOD-60444/E-GEOD-60444.processed.1.zip
storedIn:
ArrayExpress
qualifier:
gzip compressed
format:
TXT
accessType:
download
authentication:
none
authorization:
none
accessURL: https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE60444
storedIn:
Gene Expression Omnibus
qualifier:
not compressed
format:
HTML
accessType:
landing page
primary:
true
authentication:
none
authorization:
none
abbreviation:
EBI
homePage: http://www.ebi.ac.uk/
ID:
SCR:004727
name:
European Bioinformatics Institute
homePage: https://www.ebi.ac.uk/arrayexpress/
ID:
SCR:002964
name:
ArrayExpress

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