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Title: Methylome analysis of mouse cardiomyocyte de-differentiated cardiac progenitor cells      
dateReleased:
03-22-2016
description:
NimbleGen Mouse DNA Methylation 2.1M Array (CHARM design) was used to perform a DNA methylome analysis to unravel the molecular mechanism underlying the dedifferentiation and cell cycle reentry of mouse adult cardiomyocytes (ACMs). A total of six DNA samples (10 ng each) derived from population cells were subjected to whole genome amplification using Sigma WGA kit, and then 2.5 µg amplified DNA product was used for DNA methylome analysis. Three biological replicates of population ACM cells were used as controls and three biological replicates of population myocyte-derived progenitor cells (mCPCs) were used in the experimental group. Methylome microarray data using NimbleGen Mouse DNA Methylation 3x720K CpG Islands Pus RefSeq Promoter Array and DNA derived from population cells for both control cardiomyocytes and mCPCs can be found in E-MTAB-3982. Single-cell whole-transcriptome data using Affymetrix Mouse Genome 430 2.0 Array can be found in E-MTAB-3981.
privacy:
not applicable
aggregation:
instance of dataset
ID:
E-MTAB-3984
refinement:
raw
dateSubmitted:
04-28-2011
keywords:
functional genomics
dateModified:
03-22-2016
availability:
available
types:
gene expression
name:
Mus musculus
ID:
A-GEOD-10680
name:
NimbleGen Mouse 2.1M array [Feinberg_MM8_Me_HX1]
accessURL: https://www.ebi.ac.uk/arrayexpress/files/E-MTAB-3984/E-MTAB-3984.raw.1.zip
storedIn:
ArrayExpress
qualifier:
gzip compressed
format:
TXT
accessType:
download
authentication:
none
authorization:
none
accessURL: https://www.ebi.ac.uk/arrayexpress/files/E-MTAB-3984/E-MTAB-3984.processed.1.zip
storedIn:
ArrayExpress
qualifier:
gzip compressed
format:
TXT
accessType:
download
authentication:
none
authorization:
none
abbreviation:
EBI
homePage: http://www.ebi.ac.uk/
ID:
SCR:004727
name:
European Bioinformatics Institute
homePage: https://www.ebi.ac.uk/arrayexpress/
ID:
SCR:002964
name:
ArrayExpress

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