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Title: Expression data from male cynomolgus macaques exposed to 6 ppm formaldehyde      
dateReleased:
06-30-2016
description:
Exogenous formaldehyde disrupts genomic/epigenomic profiles in the rodent nose and white blood cells (WBCs) related to inflammation and immune signaling, although it does not reach the circulating blood. We aimed to compare and contrast alterations in genomic signaling in the nose and circulating blood of non-human primates exposed to formaldehyde. We used microarrays to identify transcripts that were diffentially expressed in response to formaldehyde inhalation exposure. A total of 14 primates received two consecutive days of 6-hour whole body inhalation exposures consisting of either filtered air (n = 6) or a target of 6 ppm formaldehyde (n = 8). To assess formaldehyde-induced changes in genome-wide gene expression profiles, RNA samples extracted from the nasal epithelium and circulating WBCs were labeled and hybridized to the Affymetrix Cynomolgus Macaque Gene 1.0 ST Array.
privacy:
not applicable
aggregation:
instance of dataset
ID:
E-GEOD-75759
refinement:
raw
alternateIdentifiers:
75759
keywords:
functional genomics
dateModified:
07-24-2016
availability:
available
types:
gene expression
name:
Macaca fascicularis
ID:
A-GEOD-21213
name:
[CynGene-1_0-st] Cynomolgus + Rhesus Gene 1.0 ST Array
accessURL: https://www.ebi.ac.uk/arrayexpress/files/E-GEOD-75759/E-GEOD-75759.raw.1.zip
storedIn:
ArrayExpress
qualifier:
gzip compressed
format:
TXT
accessType:
download
authentication:
none
authorization:
none
accessURL: https://www.ebi.ac.uk/arrayexpress/files/E-GEOD-75759/E-GEOD-75759.processed.1.zip
storedIn:
ArrayExpress
qualifier:
gzip compressed
format:
TXT
accessType:
download
authentication:
none
authorization:
none
accessURL: https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE75759
storedIn:
Gene Expression Omnibus
qualifier:
not compressed
format:
HTML
accessType:
landing page
primary:
true
authentication:
none
authorization:
none
abbreviation:
EBI
homePage: http://www.ebi.ac.uk/
ID:
SCR:004727
name:
European Bioinformatics Institute
homePage: https://www.ebi.ac.uk/arrayexpress/
ID:
SCR:002964
name:
ArrayExpress

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