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Title: A novel Lysyl oxidase like 2 alternative splicing LOXL2 △e13 in esophageal squamous carcinoma cells      
dateReleased:
07-03-2016
description:
A novel alternative splicing isoform of LOXL2 △e13 was expressed ubiquitously in all cell lines and ESCC tissues. In contrast to the impaired deamination enzymatic activity compared with full length LOXL2, LOXL2 △e13 showed an enhanced ability to promote cell mobility and invasiveness in ESCC cells than full length LOXL2 through a different mechanism. We used cDNA microarrays to identify genes that were differentially expressed upon LOXL2 △ e13 overexpressed. For this purpose, we selected LOXL2 △ e13, WT and empty vector control transfeced ESCC KYSE150 cell lines. Total RNA was extracted,compare the gene expression patterns between LOXL2 △e13, LOXL2 WT and empty vector control transfected cells through the Genechip Primeview Human Gene Expression Array.
privacy:
not applicable
aggregation:
instance of dataset
ID:
E-GEOD-53676
refinement:
raw
alternateIdentifiers:
53676
keywords:
functional genomics
dateModified:
12-28-2016
creators:
Guo-Qing Lv
availability:
available
types:
gene expression
name:
Homo sapiens
ID:
A-GEOD-15207
name:
GeneChip® PrimeView™ Human Gene Expression Array
accessURL: https://www.ebi.ac.uk/arrayexpress/files/E-GEOD-53676/E-GEOD-53676.raw.1.zip
storedIn:
ArrayExpress
qualifier:
gzip compressed
format:
TXT
accessType:
download
authentication:
none
authorization:
none
accessURL: https://www.ebi.ac.uk/arrayexpress/files/E-GEOD-53676/E-GEOD-53676.processed.1.zip
storedIn:
ArrayExpress
qualifier:
gzip compressed
format:
TXT
accessType:
download
authentication:
none
authorization:
none
accessURL: https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE53676
storedIn:
Gene Expression Omnibus
qualifier:
not compressed
format:
HTML
accessType:
landing page
primary:
true
authentication:
none
authorization:
none
abbreviation:
EBI
homePage: http://www.ebi.ac.uk/
ID:
SCR:004727
name:
European Bioinformatics Institute
homePage: https://www.ebi.ac.uk/arrayexpress/
ID:
SCR:002964
name:
ArrayExpress

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