Mountain View
biomedical and healthCAre Data Discovery Index Ecosystem
help Advanced Search
Title: Circulating microRNA profiles during the bovine oestrous cycle      
dateReleased:
07-29-2016
description:
Up to 50% of ovulations go undetected in modern dairy herds due to attenuated oestrus behavior and a lack of high-accuracy methods for detection of fertile oestrus. This significantly reduces overall herd productivity and constitutes a high economic burden to the dairy industry. MicroRNAs (miRNAs) are ubiquitous regulators of gene expression during both health and disease and they have been shown to regulate different reproductive processes. Extracellular miRNAs are stable and can provide useful biomarkers of tissue function; changes in circulating miRNA profiles have been reported during menstrual cycles. This study sought to establish the potential of circulating miRNAs as biomarkers of oestrus in cattle using Illumina small-RNA sequencing. In this experiment a total of 24 bovine plasma samples were analysed using Illumina miRNA sequencing. These samples were collected at three time-points during a normal oestrous cycle from each of 8 animals (Day 0, Day 8 and Day 16 after oestrus) in a repeated-measures design. Therefore this study included 8 biological replicates for each of the three time-points analysed.
privacy:
not applicable
aggregation:
instance of dataset
ID:
E-GEOD-81050
refinement:
raw
alternateIdentifiers:
81050
keywords:
functional genomics
dateModified:
08-07-2016
availability:
available
types:
gene expression
name:
Bos taurus
accessURL: https://www.ebi.ac.uk/arrayexpress/files/E-GEOD-81050/E-GEOD-81050.raw.1.zip
storedIn:
ArrayExpress
qualifier:
gzip compressed
format:
TXT
accessType:
download
authentication:
none
authorization:
none
accessURL: https://www.ebi.ac.uk/arrayexpress/files/E-GEOD-81050/E-GEOD-81050.processed.1.zip
storedIn:
ArrayExpress
qualifier:
gzip compressed
format:
TXT
accessType:
download
authentication:
none
authorization:
none
accessURL: https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE81050
storedIn:
Gene Expression Omnibus
qualifier:
not compressed
format:
HTML
accessType:
landing page
primary:
true
authentication:
none
authorization:
none
abbreviation:
EBI
homePage: http://www.ebi.ac.uk/
ID:
SCR:004727
name:
European Bioinformatics Institute
homePage: https://www.ebi.ac.uk/arrayexpress/
ID:
SCR:002964
name:
ArrayExpress

Feedback?

If you are having problems using our tools, or if you would just like to send us some feedback, please post your questions on GitHub.