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Title: Smooth muscle cell mineralocorticoid receptor regulation of vascular microRNAs with aging      
dateReleased:
07-29-2016
description:
We used a smooth muscle cell-specific mineralocorticoid receptor knockout mouse to generate young and aged MR-intact and SMC-MR-KO aortic miRNA to examine the effect of age on vascular miRNA alterations in the presence and absence of SMC-MR. For more information about the mouse model see: McCurley, A et al. Direct regulation of blood pressure by smooth muscle cell mineralocorticoid receptors. Nat Med. 2012 Sep;18(9):1429-33 Total miRNA was extracted from young (3-4 mo) and aged male (12mo) MR-intact and SMC-MR-KO mice to investigate aging-induced alterations in vascular miRNA expression
privacy:
not applicable
aggregation:
instance of dataset
ID:
E-GEOD-84960
refinement:
raw
alternateIdentifiers:
84960
keywords:
functional genomics
dateModified:
08-07-2016
availability:
available
types:
gene expression
name:
Mus musculus
ID:
A-GEOD-14613
name:
[miRNA-2_0] Affymetrix Multispecies miRNA-2_0 Array
accessURL: https://www.ebi.ac.uk/arrayexpress/files/E-GEOD-84960/E-GEOD-84960.raw.1.zip
storedIn:
ArrayExpress
qualifier:
gzip compressed
format:
TXT
accessType:
download
authentication:
none
authorization:
none
accessURL: https://www.ebi.ac.uk/arrayexpress/files/E-GEOD-84960/E-GEOD-84960.processed.1.zip
storedIn:
ArrayExpress
qualifier:
gzip compressed
format:
TXT
accessType:
download
authentication:
none
authorization:
none
accessURL: https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE84960
storedIn:
Gene Expression Omnibus
qualifier:
not compressed
format:
HTML
accessType:
landing page
primary:
true
authentication:
none
authorization:
none
abbreviation:
EBI
homePage: http://www.ebi.ac.uk/
ID:
SCR:004727
name:
European Bioinformatics Institute
homePage: https://www.ebi.ac.uk/arrayexpress/
ID:
SCR:002964
name:
ArrayExpress

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