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Title: Epigenetic Alterations in Dense Human Spermatozoa for Assisted Reproduction      
dateReleased:
08-01-2016
description:
Selected human sperms with ART technique demonstrate many changes in the genetic and epigenetic aspects. There are many evidances shown that DNA damange and histone retention ratio have significant improved after selection with different methods. These changes may relate with DNA epigenetic changes, however no evidance demonstate these relevance. In this study, MeDIP-ChIP method has been employed to detect DNA methylation loci in human sperm genome processed with density selection. Results demonstrated that DNA methylation changed in specific gene location. comparison the DNA methylation site between 3 pair human sperm DNA samples before or after density selection
privacy:
not applicable
aggregation:
instance of dataset
ID:
E-GEOD-71339
refinement:
raw
alternateIdentifiers:
71339
keywords:
functional genomics
dateModified:
08-06-2016
availability:
available
types:
gene expression
name:
Homo sapiens
ID:
A-GEOD-16353
name:
NimbleGen Human DNA Methylation 3x720K CpG Island Plus RefSeq Promoter Array��(100718_HG18_CpG_Refseq_Prom_MeDIP)
accessURL: https://www.ebi.ac.uk/arrayexpress/files/E-GEOD-71339/E-GEOD-71339.raw.1.zip
storedIn:
ArrayExpress
qualifier:
gzip compressed
format:
TXT
accessType:
download
authentication:
none
authorization:
none
accessURL: https://www.ebi.ac.uk/arrayexpress/files/E-GEOD-71339/E-GEOD-71339.processed.1.zip
storedIn:
ArrayExpress
qualifier:
gzip compressed
format:
TXT
accessType:
download
authentication:
none
authorization:
none
accessURL: https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE71339
storedIn:
Gene Expression Omnibus
qualifier:
not compressed
format:
HTML
accessType:
landing page
primary:
true
authentication:
none
authorization:
none
abbreviation:
EBI
homePage: http://www.ebi.ac.uk/
ID:
SCR:004727
name:
European Bioinformatics Institute
homePage: https://www.ebi.ac.uk/arrayexpress/
ID:
SCR:002964
name:
ArrayExpress

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