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Title: Comparative genomic hybridization by array of two epithelial cell lines (16HBE14o- and T84) and control DNA from European Hapmap cell lines      
dateReleased:
09-22-2016
description:
The aim of the project was to detect genomic regions that were normal, duplicated or deleted in these cell lines for transcription factors NFKBp50, NFkBp65, HIF1a and FAS gene which we studied. It is not clear the effects of copy number variations on allele specific assembly or disruption of master regulator transcription factors. Thus, the CNV analysis verified that 16HBE cell line, though transformed with defective simian virus, had normal copy number variations thus was a suitable source for nuclear extract to study the afore mentioned TFs. T84 showed duplications and large genomic deletions for TFs: NFkBp50 and p65. 16HBE and T84 are both epithelial cell lines type from human. 16HBE is derived from bronchial epithelium, while the T84 is derived from the colon carcinoma.
privacy:
not applicable
aggregation:
instance of dataset
ID:
E-MTAB-4194
refinement:
raw
dateSubmitted:
03-23-2014
keywords:
functional genomics
dateModified:
09-12-2016
creators:
Awah U Chidiebere
availability:
available
types:
gene expression
name:
Homo sapiens
ID:
A-MEXP-1134
name:
Agilent Human Genome CGH Microarray 44K 014950 G4426B
accessURL: https://www.ebi.ac.uk/arrayexpress/files/E-MTAB-4194/E-MTAB-4194.raw.1.zip
storedIn:
ArrayExpress
qualifier:
gzip compressed
format:
TXT
accessType:
download
authentication:
none
authorization:
none
accessURL: https://www.ebi.ac.uk/arrayexpress/files/E-MTAB-4194/E-MTAB-4194.processed.1.zip
storedIn:
ArrayExpress
qualifier:
gzip compressed
format:
TXT
accessType:
download
authentication:
none
authorization:
none
abbreviation:
EBI
homePage: http://www.ebi.ac.uk/
ID:
SCR:004727
name:
European Bioinformatics Institute
homePage: https://www.ebi.ac.uk/arrayexpress/
ID:
SCR:002964
name:
ArrayExpress

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