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Title: RIP-seq analysis of Isw1 interacting transcripts      
dateReleased:
11-17-2016
description:
This experiment captures the poly(A)RNAs co-immunoprecipated with Isw1 in WT and npl3-1 cells. Chromatin remodelers play an essential role in regulating DNA transaction processes. The yeast chromatin remodeling complex ISW1 displays an unexpected function in nuclear mRNP surveillance, retaining premature mRNPs in proximity to their transcription site. This activity of ISW1 requires its recruitment onto chromatin, its interaction with mRNPs but not its nucleosome sliding activity. In npl3-1 cells, mRNA export is compromised resulting in an increased association of mRNAs with Isw1.
privacy:
not applicable
aggregation:
instance of dataset
ID:
E-MTAB-4826
refinement:
raw
dateSubmitted:
08-25-2015
keywords:
functional genomics
dateModified:
11-04-2016
creators:
Anna BABOUR
availability:
available
types:
gene expression
name:
Saccharomyces cerevisiae
accessURL: https://www.ebi.ac.uk/arrayexpress/files/E-MTAB-4826/E-MTAB-4826.raw.1.zip
storedIn:
ArrayExpress
qualifier:
gzip compressed
format:
TXT
accessType:
download
authentication:
none
authorization:
none
accessURL: https://www.ebi.ac.uk/arrayexpress/files/E-MTAB-4826/E-MTAB-4826.processed.1.zip
storedIn:
ArrayExpress
qualifier:
gzip compressed
format:
TXT
accessType:
download
authentication:
none
authorization:
none
abbreviation:
EBI
homePage: http://www.ebi.ac.uk/
ID:
SCR:004727
name:
European Bioinformatics Institute
homePage: https://www.ebi.ac.uk/arrayexpress/
ID:
SCR:002964
name:
ArrayExpress

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