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Title: Transcription profiling by array of pig peripheral blood mononuclear cells (PBMCs) vaccinated against porcine reproductive and respiratory syndrome (PRRS) to identify molecular pathways associated with "good" and "bad" PRRSV vaccine responders      
dateReleased:
11-28-2016
description:
The initial interaction of porcine reproductive and respiratory virus (PRRSV) with the immune system is of critical importance for immunological and clinical outcomes. PRRSV infection is associated with inefficient or aberrant immune responses: weak and delayed neutralizing antibody responses and erratic IFN-γ producing T-cells specific response. The lack of vaccine correlates capable of predicting protection has largely hampered the development of new efficacious PRRS vaccines. The objective of this study was to determine if systems biology (1) could be used to identify molecular pathways associated with “good” and “bad” PRRSV vaccine responders in terms of their intensity of IFN- γ secreting cell responses.
privacy:
not applicable
aggregation:
instance of dataset
ID:
E-MTAB-3237
refinement:
raw
dateSubmitted:
08-16-2013
keywords:
functional genomics
dateModified:
11-27-2016
creators:
Tahar AIT-ALI
availability:
available
types:
gene expression
name:
Sus scrofa
ID:
A-AFFY-189
name:
Affymetrix Porcine Snowball Array
accessURL: https://www.ebi.ac.uk/arrayexpress/files/E-MTAB-3237/E-MTAB-3237.raw.1.zip
storedIn:
ArrayExpress
qualifier:
gzip compressed
format:
TXT
accessType:
download
authentication:
none
authorization:
none
accessURL: https://www.ebi.ac.uk/arrayexpress/files/E-MTAB-3237/E-MTAB-3237.processed.1.zip
storedIn:
ArrayExpress
qualifier:
gzip compressed
format:
TXT
accessType:
download
authentication:
none
authorization:
none
abbreviation:
EBI
homePage: http://www.ebi.ac.uk/
ID:
SCR:004727
name:
European Bioinformatics Institute
homePage: https://www.ebi.ac.uk/arrayexpress/
ID:
SCR:002964
name:
ArrayExpress

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