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Title: The Sinorhizobium meliloti SmYbeY-dependent transcriptome probed with Sm14kOLI microarrays      
dateReleased:
12-08-2016
description:
In this experiment we have compared the transcriptome of the S. meliloti Sm2B3001 strain and that of a mutant derivative lacking the gene encoding the almost ubiquitous bacterial endoribonuclease YbeY. Both, the parent and mutant strains were grown to either exponential or stationary phases in complete TY medium. Total RNA of parent and mutant strains (four replicates in each growth condition) were probed by competitive hybridization on Sm14kOLI microarrays. SmYbeY loss-of-function compromised expression of core energy and RNA metabolism genes, whilst promoting accumulation of motility, late symbiotic and transport mRNAs. Up-regulated transcripts are putative SmYbeY substrates representing both bulk and sRNA-regulated mRNAs.
privacy:
not applicable
aggregation:
instance of dataset
ID:
E-MTAB-5233
refinement:
raw
dateSubmitted:
10-31-2014
keywords:
functional genomics
dateModified:
12-08-2016
creators:
José I Jiménez-Zurdo
availability:
available
types:
gene expression
name:
Sinorhizobium meliloti
name:
genetic modification design
ID:
A-MEXP-1760
name:
Sm14kOLIGO
accessURL: https://www.ebi.ac.uk/arrayexpress/files/E-MTAB-5233/E-MTAB-5233.raw.1.zip
storedIn:
ArrayExpress
qualifier:
gzip compressed
format:
TXT
accessType:
download
authentication:
none
authorization:
none
accessURL: https://www.ebi.ac.uk/arrayexpress/files/E-MTAB-5233/E-MTAB-5233.processed.1.zip
storedIn:
ArrayExpress
qualifier:
gzip compressed
format:
TXT
accessType:
download
authentication:
none
authorization:
none
abbreviation:
EBI
homePage: http://www.ebi.ac.uk/
ID:
SCR:004727
name:
European Bioinformatics Institute
homePage: https://www.ebi.ac.uk/arrayexpress/
ID:
SCR:002964
name:
ArrayExpress

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